Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781411 | 1.00 | CHRNB4 (0.46) | CHRNB4CHRNA3HSD17B2SLC6A2SLC6A4 | |
| SCHEMBL4725436 | 1.00 | CHRNB4 (0.46) | CHRNB4CHRNA3HSD17B2SLC6A2SLC6A4 | |
| SCHEMBL6819282 | 0.91 | CHRNB4 (0.50) | CHRNB4CHRNA3 | |
| SCHEMBL1797592 | 0.91 | CHRNB4 (0.50) | CHRNB4CHRNA3 | |
| SCHEMBL1797593 | 0.91 | CHRNB4 (0.50) | CHRNB4CHRNA3 | |
| SCHEMBL13403259 | 0.89 | CHRNB4 (0.49) | CHRNB4CHRNA3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6648223 | 0.86 | CHRNB4 (0.55) | CHRNB4CHRNA3 | |
| SCHEMBL8222689 | 0.86 | CHRNB4 (0.48) | CHRNB4CHRNA3 | |
| SCHEMBL4780734 | 0.83 | SLC6A2 (0.43) | CHRNB4CHRNA3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4794244 | 0.83 | SLC6A2 (0.43) | CHRNB4CHRNA3SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |