SCHEMBL4725754

SCHEMBL4725754

CCCc1c(OCC)c(NC(C)=O)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12

nearest known ligand 0.91

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE11A Q9HCR9 13/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4728772 0.95 PDE11A (1.00) PDE11A
SCHEMBL4725313 0.89 PDE11A (0.88) PDE11A
SCHEMBL4726040 0.88 PDE11A (0.87) PDE11A
SCHEMBL4726094 0.88 PDE11A (1.00) PDE11A
SCHEMBL4725311 0.88 PDE11A (1.00) PDE11A
SCHEMBL4727226 0.87 PDE11A (0.89) PDE11A
SCHEMBL4726287 0.87 PDE11A (0.84) PDE11A
SCHEMBL4726826 0.86 PDE11A (1.00) PDE11A
SCHEMBL4726290 0.86 PDE11A (0.88) PDE11A
SCHEMBL4726772 0.86 PDE11A (0.88) PDE11A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008020711-A1 QUINAZOLINE DERIVATIVE AS PHOSPHODIESTERASE INHIBITOR AND A PROCESS FOR PREPARING THE SAME CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2008-02-21 WO claimed
WO-2008020711-A1 QUINAZOLINE DERIVATIVE AS PHOSPHODIESTERASE INHIBITOR AND A PROCESS FOR PREPARING THE SAME CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2008-02-21 WO disclosed