Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779978 | 0.87 | GRIN2D (0.43) | L3MBTL1KDM4CKDM4EALDH1A1HSD17B10 | |
| SCHEMBL23337439 | 0.80 | KDM4E (0.44) | L3MBTL1TP53KDM4CKDM4EALDH1A1 | |
| SCHEMBL4725397 | 0.79 | KDM5B (0.43) | TP53KDM4CKDM4EALDH1A1LMNA | |
| SCHEMBL6829325 | 0.77 | CHRM1 (0.46) | HDAC6L3MBTL1CHRM1PARP1PARP2 | |
| SCHEMBL9588111 | 0.77 | CHRM1 (0.49) | HDAC6L3MBTL1CHRM1PARP1PARP2 | |
| SCHEMBL7260709 | 0.74 | TSHR (0.49) | TP53PARP1KDM4EALDH1A1LMNA | |
| SCHEMBL5271758 | 0.74 | KDM4E (0.44) | L3MBTL1KDM4CKDM4EALDH1A1LMNA | |
| SCHEMBL4365104 | 0.73 | ELANE (0.42) | TP53PARP1KDM4CALDH1A1ELANE | |
| SCHEMBL28172168 | 0.73 | KDM4C (0.42) | TP53KDM4CKDM4EALDH1A1LMNA | |
| SCHEMBL6946399 | 0.73 | CHRM1 (0.55) | HDAC6TP53CHRM1PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008012852-A1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II ANTAGONISTS | S.I.M.S. S.r.l. - SOCIETÀ ITALIANA MEDICINALI SCANDICCI (IT) | 2008-01-31 | — | — | WO | claimed |
| WO-2008012852-A1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II ANTAGONISTS | S.I.M.S. S.r.l. - SOCIETÀ ITALIANA MEDICINALI SCANDICCI (IT) | 2008-01-31 | — | — | WO | disclosed |