SCHEMBL4726063

SCHEMBL4726063

C=CCc1c(OC)c(NCCCC)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE11A Q9HCR9 11/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4726058 0.88 PDE11A (0.90) PDE11A
SCHEMBL4726824 0.88 PDE11A (0.73) PDE11A
SCHEMBL4726755 0.85 PDE11A (1.00) PDE11A
SCHEMBL4726801 0.85 PDE11A (0.85) PDE11A
SCHEMBL4726822 0.83 PDE11A (0.81) PDE11A
SCHEMBL4729299 0.83 PDE11A (0.80) PDE11A
SCHEMBL4725872 0.82 PDE11A (0.74) PDE11A
SCHEMBL4726006 0.81 PDE11A (0.69) PDE11A
SCHEMBL4725935 0.79 PDE11A (0.82) PDE11A
SCHEMBL4726121 0.79 PDE11A (0.77) PDE11A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008020711-A1 QUINAZOLINE DERIVATIVE AS PHOSPHODIESTERASE INHIBITOR AND A PROCESS FOR PREPARING THE SAME CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2008-02-21 WO claimed
WO-2008020711-A1 QUINAZOLINE DERIVATIVE AS PHOSPHODIESTERASE INHIBITOR AND A PROCESS FOR PREPARING THE SAME CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2008-02-21 WO disclosed