Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726370 | 1.00 | HSD17B10 (0.39) | HSD17B10HTTTSHRPPARAPPARG | |
| SCHEMBL4725557 | 0.91 | TSHR (0.39) | HTTTSHRPPARAPPARGSMN1; SMN2 | |
| SCHEMBL4725558 | 0.91 | TSHR (0.39) | HTTTSHRPPARAPPARGSMN1; SMN2 | |
| SCHEMBL4729074 | 0.88 | HTT (0.40) | HSD17B10HTTTSHRPPARAPPARG | |
| SCHEMBL4729069 | 0.88 | HTT (0.40) | HSD17B10HTTTSHRPPARAPPARG | |
| SCHEMBL4727908 | 0.86 | PPARA (0.41) | PPARAPPARGSMN1; SMN2ALDH1A1PPARD | |
| SCHEMBL4727910 | 0.86 | PPARA (0.41) | PPARAPPARGSMN1; SMN2ALDH1A1PPARD | |
| SCHEMBL4727006 | 0.85 | MCL1 (0.43) | HSD17B10HTTTSHRPPARAPPARG | |
| SCHEMBL4727000 | 0.85 | MCL1 (0.43) | HSD17B10HTTTSHRPPARAPPARG | |
| SCHEMBL4729739 | 0.83 | SMN1; SMN2 (0.41) | HSD17B10HTTTSHRPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |