Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 20/20 | 0.73 |
| ▸ | HRH1 | P35367 | 5/20 | 0.68 |
| ▸ | HTR2B | P41595 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3572121 | 0.88 | SSTR5 (0.56) | SSTR5HRH1HTR2B | |
| SCHEMBL1121611 | 0.87 | SSTR5 (0.75) | SSTR5HRH1HTR2B | |
| SCHEMBL1121390 | 0.86 | SSTR5 (0.65) | SSTR5HRH1HTR2B | |
| SCHEMBL1121288 | 0.86 | SSTR5 (0.61) | SSTR5HRH1HTR2B | |
| SCHEMBL1121614 | 0.86 | SSTR5 (0.60) | SSTR5HRH1HTR2B | |
| SCHEMBL1121454 | 0.86 | SSTR5 (0.58) | SSTR5HRH1HTR2B | |
| SCHEMBL1122193 | 0.85 | SSTR5 (0.58) | SSTR5HRH1HTR2B | |
| SCHEMBL1380401 | 0.84 | SSTR5 (1.00) | SSTR5HRH1HTR2B | |
| SCHEMBL3570050 | 0.84 | SSTR5 (1.00) | SSTR5HRH1HTR2B | |
| SCHEMBL3572493 | 0.84 | SSTR5 (1.00) | SSTR5HRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924579-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025897-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | disclosed |