Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 11/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 12/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 10/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210000 | 0.75 | CHRM3 (0.43) | CHRM3CHRM2CHRM1KCNH2CYP2D6 | |
| SCHEMBL4727200 | 0.75 | CHRM3 (0.35) | CHRM3CHRM2CHRM1KCNH2CYP2D6 | |
| SCHEMBL4725321 | 0.74 | HRH1 (0.39) | CHRM3CHRM2CHRM1KCNH2CYP2D6 | |
| SCHEMBL4727371 | 0.74 | CHRM3 (0.43) | CHRM3CHRM2CHRM1KCNH2CYP2D6 | |
| SCHEMBL4740717 | 0.74 | CHRM3 (0.43) | CHRM3CHRM2CHRM1KCNH2CYP2D6 | |
| SCHEMBL4779634 | 0.74 | CHRM3 (0.39) | CHRM3CHRM2CHRM1KCNH2CYP2D6 | |
| Bromide SCHEMBL4725231 | 0.73 | CHRM3 (0.38) | CHRM3CHRM2CHRM1KCNH2CYP2D6 | |
| SCHEMBL4726224 | 0.73 | CHRM2 (0.37) | CHRM3CHRM2CHRM1KCNH2CYP2D6 | |
| Bromide SCHEMBL4728212 | 0.72 | CHRM2 (0.36) | CHRM3CHRM2CHRM1KCNH2CYP2D6 | |
| SCHEMBL4727450 | 0.71 | CHRM3 (0.35) | CHRM3CHRM2CHRM1KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |