Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533185 | 0.85 | MEN1 (0.37) | MEN1CYP2C19KMT2A | |
| SCHEMBL2879085 | 0.81 | MEN1 (0.34) | MEN1CYP2C19KMT2A | |
| SCHEMBL533323 | 0.81 | CYP11B1 (0.35) | MEN1CYP2C19KMT2A | |
| SCHEMBL9911674 | 0.81 | CYP2C19 (0.44) | MEN1CYP2C19KMT2A | |
| SCHEMBL5946282 | 0.74 | CYP2C19 (0.62) | MEN1CYP2C19KMT2A | |
| SCHEMBL6059122 | 0.72 | — | — | |
| SCHEMBL7950469 | 0.70 | — | — | |
| SCHEMBL25239780 | 0.70 | TSHR (0.37) | — | |
| SCHEMBL1725362 | 0.70 | MAPT (0.50) | MEN1CYP2C19KMT2A | |
| SCHEMBL11498901 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244718-A1 | REPROGRAMMING OF PLURIPOTENT STEM CELLS FOR IMPROVED CONTROL OF THEIR DIFFERENTIATION PATHWAYS | ETH ZURICH (CH) | 2016-08-25 | — | — | US | disclosed |
| EP-3052617-A1 | REPROGRAMMING OF PLURIPOTENT STEM CELLS FOR IMPROVED CONTROL OF THEIR DIFFERENTIATION PATHWAYS | ETH Zurich (CH) | 2016-08-10 | — | — | EP | disclosed |
| EP-2576817-B1 | METHODS OF DIAGNOSING ALGESIA | SANOFI SA (FR) | 2016-07-27 | — | — | EP | disclosed |
| EP-2547789-B1 | Methods and uses relating to the identification of compound involved in pain as well as methods of diagnosing algesia | SANOFI SA (FR) | 2015-07-22 | — | — | EP | disclosed |
| WO-2015049342-A1 | REPROGRAMMING OF PLURIPOTENT STEM CELLS FOR IMPROVED CONTROL OF THEIR DIFFERENTIATION PATHWAYS | ETH ZURICH (CH) | 2015-04-09 | — | — | WO | disclosed |
| EP-2857501-A1 | Reprogramming of pluripotent stem cells for improved control of their differentiation pathways | ETH Zurich (CH) | 2015-04-08 | — | — | EP | disclosed |
| US-8835359-B2 | Methods and uses relating to the identification of compound involved in pain as well as methods of diagnosing algesia | SANOFI (FR) | 2014-09-16 | — | — | US | disclosed |
| US-8673823-B2 | Methods and uses relating to the identification of compound involved in pain as well as methods of diagnosing algesia | SANOFI (FR) | 2014-03-18 | — | — | US | disclosed |
| US-20130274120-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND INVOLVED IN PAIN AS WELL AS METHODS OF DIAGNOSING ALGESIA | SANOFI (FR) | 2013-10-17 | — | — | US | disclosed |
| US-20130157890-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND INVOLVED IN PAIN AS WELL AS METHODS OF DIAGNOSING ALGESIA | SANOFI (FR) | 2013-06-20 | — | — | US | disclosed |
| WO-2011113891-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND INVOLVED IN PAIN AS WELL AS METHODS OF DIAGNOSING ALGESIA | SANOFI-AVENTIS (FR) | 2011-09-22 | — | — | WO | disclosed |
| WO-2011113890-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND INVOLVED IN PAIN AS WELL AS METHODS OF DIAGNOSING ALGESIA | SANOFI (FR) | 2011-09-22 | — | — | WO | disclosed |
| WO-2011113888-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND INVOLVED IN PAIN AS WELL AS METHODS OF DIAGNOSING ALGESIA | SANOFI-AVENTIS (FR) | 2011-09-22 | — | — | WO | disclosed |
| WO-2011089194-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND INVOLVED IN PAIN AS WELL AS METHODS OF DIAGNOSING ALGESIA | SANOFI-AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011089192-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND INVOLVED IN PAIN AS WELL AS METHODS OF DIAGNOSING ALGESIA | SANOFI-AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |
| EP-2348128-A1 | Methods and uses relating to the identification of compound involved in pain as well as methods of diagnosing algesia | SANOFI (FR) | 2011-07-27 | — | — | EP | disclosed |
| EP-2348129-A1 | Methods and uses relating to the identification of compound involved in pain as well as methods of diagnosing algesia | SANOFI (FR) | 2011-07-27 | — | — | EP | disclosed |
| EP-2348130-A1 | Methods and uses relating to the identification of compound involved in pain as well as methods of diagnosing algesia | SANOFI (FR) | 2011-07-27 | — | — | EP | disclosed |
| WO-2011054900-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND INVOLVED IN PAIN AS WELL AS METHODS OF DIAGNOSING ALGESIA | SANOFI-AVENTIS (FR) | 2011-05-12 | — | — | WO | disclosed |
| EP-2320236-A1 | Methods and uses relating to the identification of compound involved in pain as well as methods of diagnosing algesia | Sanofi-aventis (FR) | 2011-05-11 | — | — | EP | disclosed |