Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4727384 | 0.99 | CHRM3 (0.35) | CHRM3KCNH2CHRM2CHRM1SLC6A3 | |
| SCHEMBL4727450 | 0.96 | CHRM3 (0.35) | CHRM3KCNH2CHRM2CHRM1SLC6A3 | |
| SCHEMBL4779634 | 0.90 | CHRM3 (0.39) | CHRM3KCNH2CHRM2CHRM1SLC6A3 | |
| Bromide SCHEMBL4725231 | 0.89 | CHRM3 (0.38) | CHRM3KCNH2CHRM2CHRM1SLC6A3 | |
| SCHEMBL4726718 | 0.85 | CHRM3 (0.35) | CHRM3KCNH2CHRM2CHRM1SLC6A3 | |
| SCHEMBL4726613 | 0.85 | TSHR (0.35) | CHRM3KCNH2CHRM2CHRM1SLC6A3 | |
| SCHEMBL4726751 | 0.84 | POLB (0.37) | CHRM3KCNH2CHRM2CHRM1SLC6A3 | |
| SCHEMBL523560 | 0.81 | CYP19A1 (0.35) | CHRM3KCNH2CHRM2CHRM1SLC6A3 | |
| SCHEMBL523559 | 0.81 | CYP19A1 (0.35) | CHRM3KCNH2CHRM2CHRM1SLC6A3 | |
| Bromide SCHEMBL1179774 | 0.80 | CYP19A1 (0.35) | CHRM3KCNH2CHRM2CHRM1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | claimed |
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |