Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL804234 | 0.83 | CYP2D6 (0.67) | CYP2D6KMT2ALMNAHIF1AKDM4E | |
| SCHEMBL1646857 | 0.83 | CYP2D6 (0.67) | CYP2D6KMT2ALMNAHIF1AKDM4E | |
| SCHEMBL1644948 | 0.83 | CYP2D6 (0.67) | CYP2D6KMT2ALMNAHIF1AKDM4E | |
| SCHEMBL5158960 | 0.83 | CYP2D6 (0.73) | CYP2D6KMT2ALMNASRCMAPK1 | |
| SCHEMBL66944 | 0.83 | CYP2D6 (0.73) | CYP2D6KMT2ALMNASRCMAPK1 | |
| SCHEMBL193565 | 0.83 | CYP2D6 (0.73) | CYP2D6KMT2ALMNASRCMAPK1 | |
| Hydrochloric Acid SCHEMBL7363508 | 0.82 | CYP2D6 (0.64) | CYP2D6KMT2ALMNAHIF1AKDM4E | |
| Hydrochloric Acid SCHEMBL10582883 | 0.81 | CYP2D6 (0.70) | CYP2D6KMT2ALMNASRCMAPK1 | |
| Hydrochloric Acid SCHEMBL10872012 | 0.81 | CYP2D6 (0.70) | CYP2D6KMT2ALMNASRCMAPK1 | |
| Acetic Acid SCHEMBL1646869 | 0.80 | CYP2D6 (0.61) | CYP2D6KMT2ALMNAHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008012852-A1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II ANTAGONISTS | S.I.M.S. S.r.l. - SOCIETÀ ITALIANA MEDICINALI SCANDICCI (IT) | 2008-01-31 | — | — | WO | claimed |
| WO-2008012852-A1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II ANTAGONISTS | S.I.M.S. S.r.l. - SOCIETÀ ITALIANA MEDICINALI SCANDICCI (IT) | 2008-01-31 | — | — | WO | disclosed |