SCHEMBL4728116

SCHEMBL4728116

CCC(Oc1ccc(C(CC2CCCCC2)=NO)cc1C)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 4/20 0.54
PDE4A P27815 3/20 0.42
PDE4B Q07343 3/20 0.42
PDE4C Q08493 3/20 0.42
PDE4D Q08499 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
PPARG P37231 3/20 0.37
P2RX3 P56373 2/20 0.36
POLB P06746 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4730561 0.99 PPARA (0.53) PPARAPDE4APDE4BPDE4CPDE4D
SCHEMBL4727866 0.99 PPARA (0.53) PPARAPDE4APDE4BPDE4CPDE4D
SCHEMBL4728547 0.83 PPARA (0.54) PPARAPDE4APDE4BPDE4CPDE4D
SCHEMBL4728546 0.83 PPARA (0.54) PPARAPDE4APDE4BPDE4CPDE4D
SCHEMBL4728216 0.81 PPARA (0.50) PPARASMN1; SMN2PPARGPTGDR2
SCHEMBL4730161 0.81 PPARA (0.44) PPARAPDE4APDE4BPDE4CPDE4D
SCHEMBL4728230 0.81 PPARA (0.44) PPARAPDE4APDE4BPDE4CPDE4D
SCHEMBL4729835 0.80 PPARA (0.43) PPARAPDE4APDE4BPDE4CPDE4D
SCHEMBL4729729 0.78 PPARA (0.50) PPARASMN1; SMN2PPARGPTGDR2
SCHEMBL4729125 0.76 PPARA (0.45) PPARASMN1; SMN2PPARGP2RX3PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO claimed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed