SCHEMBL4728765

SCHEMBL4728765

CN(C)CC[C@H](NC(=O)c1ccc(-c2ccc3ccccc3c2)cc1)c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4733914 1.00 UTS2R (1.00) UTS2R
SCHEMBL4731767 0.95 UTS2R (1.00) UTS2R
SCHEMBL4731069 0.95 UTS2R (1.00) UTS2R
SCHEMBL4731176 0.92 UTS2R (1.00) UTS2R
SCHEMBL4729680 0.92 UTS2R (1.00) UTS2R
SCHEMBL4731252 0.91 UTS2R (1.00) UTS2R
SCHEMBL4731967 0.91 UTS2R (1.00) UTS2R
SCHEMBL4734969 0.91 UTS2R (1.00) UTS2R
SCHEMBL4731280 0.91 UTS2R (1.00) UTS2R
Hydrochloric Acid SCHEMBL4731697 0.90 UTS2R (1.00) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008057543-A2 UII-MODULATING COMPOUNDS AND THEIR USE ACADIA PHARMACEUTICALS INC. (US) 2008-05-15 WO claimed
WO-2008057543-A2 UII-MODULATING COMPOUNDS AND THEIR USE ACADIA PHARMACEUTICALS INC. (US) 2008-05-15 WO disclosed