Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 10/20 | 0.74 |
| ▸ | ACHE | P22303 | 4/20 | 0.72 |
| ▸ | BACE1 | P56817 | 4/20 | 0.72 |
| ▸ | AURKA | O14965 | 3/20 | 0.69 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.64 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726963 | 0.98 | KIT (0.74) | KITACHEBACE1AURKAPDGFRB | |
| SCHEMBL23762351 | 0.91 | ENPP1 (0.68) | KITACHEBACE1AURKAPDGFRB | |
| SCHEMBL29055085 | 0.90 | PDGFRB (0.69) | KITACHEBACE1AURKAPDGFRB | |
| Hydrochloric Acid SCHEMBL30080215 | 0.90 | ENPP1 (0.67) | KITACHEBACE1AURKAPDGFRB | |
| Hydrochloric Acid SCHEMBL23726648 | 0.90 | ENPP1 (0.67) | KITACHEBACE1AURKAPDGFRB | |
| SCHEMBL23762457 | 0.88 | ENPP1 (0.65) | KITACHEBACE1AURKAPDGFRB | |
| SCHEMBL23726611 | 0.85 | TLR9 (0.71) | KITACHEBACE1AURKAPDGFRB | |
| SCHEMBL30080195 | 0.85 | TLR9 (0.71) | KITACHEBACE1AURKAPDGFRB | |
| SCHEMBL16109511 | 0.85 | KIT (1.00) | KIT | |
| SCHEMBL23727309 | 0.85 | ENPP1 (0.61) | KITACHEBACE1AURKAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020302-A2 | HETEROAROMATIC QUINOLINE-BASED COMPOUNDS AS PHOSPHODIESTERASE (PDE) INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | disclosed |