⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3291489 | 0.98 | — | — | |
| SCHEMBL2406914 | 0.70 | — | — | |
| SCHEMBL10667405 | 0.70 | — | — | |
| SCHEMBL30982574 | 0.69 | GSK3A (0.35) | — | |
| Hydrochloric Acid SCHEMBL10721534 | 0.67 | GSK3A (0.33) | — | |
| SCHEMBL5397009 | 0.67 | — | — | |
| SCHEMBL30983029 | 0.65 | — | — | |
| SCHEMBL3666439 | 0.65 | KDM4E (0.41) | — | |
| SCHEMBL31055644 | 0.65 | GSK3A (0.36) | — | |
| SCHEMBL31693453 | 0.64 | GSK3A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716366-B | 3-hydroxypyridin-4-one derivatives and application thereof in inhibiting iron death of renal cells | 浙江大学 | 2023-12-26 | — | — | CN | claimed |
| CN-1473153-A | Hetero-anellated ortho-aminophenols | 克莱里安特财务(BVI)有限公司 | 2004-02-04 | — | — | CN | claimed |
| US-20240200049-A1 | COMPOSITIONS AND METHODS OF USE THEREOF FOR MAKING POLYPEPTIDES WITH MANY INSTANCES OF NONSTANDARD AMINO ACIDS | YALE UNIVERSITY | 2024-06-20 | — | — | US | disclosed |
| CN-114832119-B | Radioactive gel microsphere and preparation method and application thereof | 苏州大学 | 2024-02-09 | — | — | CN | disclosed |
| US-11649446-B2 | Compositions and methods of use thereof for making polypeptides with many instances of nonstandard amino acids | YALE UNIVERSITY (US) | 2023-05-16 | — | — | US | disclosed |
| CN-115960109-A | Preparation and application of fused-ring SHP2 phosphatase inhibitor | 药雅科技(上海)有限公司 | 2023-04-14 | — | — | CN | disclosed |
| WO-2022237676-A1 | PREPARATION AND APPLICATION OF SHP2 PHOSPHATASE INHIBITOR | 药雅科技(上海)有限公司 | 2022-11-17 | — | — | WO | disclosed |
| CN-115340561-A | Preparation and application of SHP2 phosphatase fused ring inhibitor | 药雅科技(上海)有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-115340559-A | Preparation and application of SHP2 phosphatase heterocyclic inhibitor | 药雅科技(上海)有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-114832119-A | Radioactive gel microsphere and preparation method and application thereof | 苏州大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-114716366-A | 3-hydroxypyridine-4-ketone derivatives and application thereof in inhibition of renal cell iron death | 浙江大学 | 2022-07-08 | — | — | CN | disclosed |
| EP-0107458-B1 | PHARMACEUTICAL COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-07-29 | — | — | EP | disclosed |
| US-4650793-A | NITROGEN-SUBSTITUTED | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-03-17 | — | — | US | disclosed |
| EP-0094149-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING A COMPLEX OF IRON WITH N-SUBSTITUTED 3-HYDROXYPYRID-2-ONE OR -4-ONE DERIVATIVES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-09-10 | — | — | EP | disclosed |
| US-4575502-A | IRON DEFICIENCY ANEMIA | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-03-11 | — | — | US | disclosed |
| EP-0159917-A2 | Pharmaceutical composition containing a hydroxypyrone-iron complex | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-10-30 | — | — | EP | disclosed |
| US-4550101-A | Iron complexes of hydroxy pyridones useful for treating iron deficiency anemia | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-10-29 | — | — | US | disclosed |
| EP-0120670-A1 | Iron III complexes of hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |
| EP-0107458-A1 | Pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-05-02 | — | — | EP | disclosed |
| EP-0094149-A2 | Pharmaceutical compositions containing a complex of iron with N-substituted 3-hydroxypyrid-2-one or -4-one derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-11-16 | — | — | EP | disclosed |