Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.57 |
| ▸ | SCARB1 | Q8WTV0 | 6/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016327 | 0.89 | MAPK14 (0.54) | MAPK14SCARB1BRAF | |
| SCHEMBL690060 | 0.88 | MAPK14 (0.53) | MAPK14SCARB1BRAF | |
| Hydrochloric Acid SCHEMBL689965 | 0.86 | MAPK14 (0.52) | MAPK14SCARB1BRAF | |
| SCHEMBL5311588 | 0.86 | MAPK14 (0.52) | MAPK14SCARB1BRAF | |
| SCHEMBL10231144 | 0.84 | AKR1C3 (0.45) | MAPK14 | |
| SCHEMBL1846611 | 0.83 | MAPK14 (0.63) | MAPK14SCARB1GSK3ABRAF | |
| SCHEMBL10104416 | 0.81 | MAPK14 (0.53) | MAPK14SCARB1BRAF | |
| SCHEMBL16139154 | 0.81 | MAPK14 (0.63) | MAPK14SCARB1GSK3ABRAF | |
| SCHEMBL16138966 | 0.80 | MAPK14 (0.53) | MAPK14SCARB1BRAF | |
| SCHEMBL19054703 | 0.80 | MAPK14 (0.55) | MAPK14SCARB1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |