Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 1.00 |
| ▸ | CNR1 | P21554 | 6/20 | 0.80 |
| ▸ | RRM2 | P31350 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732946 | 0.89 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL4730649 | 0.88 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL4729964 | 0.88 | CNR2 (0.82) | CNR2CNR1 | |
| SCHEMBL14206427 | 0.87 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL4732901 | 0.86 | CNR2 (0.79) | CNR2CNR1 | |
| SCHEMBL4729060 | 0.86 | CNR2 (0.79) | CNR2CNR1 | |
| SCHEMBL4731520 | 0.86 | CNR2 (0.79) | CNR2CNR1 | |
| SCHEMBL14207378 | 0.85 | CNR2 (0.77) | CNR2CNR1 | |
| SCHEMBL4729643 | 0.85 | CNR2 (0.77) | CNR2CNR1 | |
| SCHEMBL4733803 | 0.85 | CNR2 (0.92) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |