SCHEMBL4730148

SCHEMBL4730148

Cc1cc(CC(=NOCc2ccc(C(F)(F)F)cc2)c2ccccc2)ccc1OCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.56
PPARA Q07869 5/20 0.56
PPARG P37231 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4726549 0.92 PPARD (0.61) PPARDPPARAPPARG
SCHEMBL4726545 0.92 PPARD (0.61) PPARDPPARAPPARG
SCHEMBL15543950 0.92 PPARD (0.49) PPARDPPARAPPARG
SCHEMBL4730650 0.92 PPARD (0.55) PPARDPPARAPPARG
SCHEMBL4730655 0.89 PPARD (0.53) PPARDPPARAPPARG
SCHEMBL4730648 0.87 PPARD (0.59) PPARDPPARAPPARG
SCHEMBL4726295 0.86 PPARD (0.77) PPARDPPARAPPARG
SCHEMBL15543358 0.85 GAA (0.48) PPARDPPARAPPARG
SCHEMBL16468780 0.85 PPARD (0.53) PPARDPPARAPPARG
SCHEMBL15543948 0.85 PPARD (0.53) PPARDPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2864309-A1 COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES Cadila Healthcare Limited (IN) 2015-04-29 EP disclosed
WO-2014002105-A1 COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES CADILA HEALTHCARE LIMITED (IN) 2014-01-03 WO disclosed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed