Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 9/20 | 0.57 |
| ▸ | RBP4 | P02753 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472990 | 0.86 | SCD (0.57) | SCDRBP4TTR | |
| SCHEMBL473059 | 0.85 | SCD (0.73) | SCD | |
| SCHEMBL473009 | 0.84 | SCD (0.71) | SCD | |
| SCHEMBL9994208 | 0.82 | SCD (0.61) | SCD | |
| SCHEMBL14870441 | 0.80 | SCD (0.60) | SCD | |
| SCHEMBL3592041 | 0.76 | SCD (0.61) | SCDRBP4TTR | |
| SCHEMBL473051 | 0.76 | SCD (0.61) | SCD | |
| SCHEMBL4543744 | 0.75 | SCD (0.62) | SCDRBP4TTR | |
| SCHEMBL473002 | 0.74 | SCD (0.67) | SCD | |
| SCHEMBL13870720 | 0.74 | SCD (0.74) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099793-B1 | AZACYCLOALKANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK CANADA INC (CA) | 2012-02-01 | — | — | EP | disclosed |
| US-8063224-B2 | [5-(5-{4-[2-(Trifluoromethyl)phenoxy]piperidin-1-yl}-1,3,4-thiadiazol-2-yl)-2H-tetrazol-2-yl]acetic acid; metabolic disorders,antidiabetic, hypoglycemic agent; obesity, insulin resistance, liver steatosis, atherosclerosis, neurological disease, dyslipidemia, hyperlipidemia, low HDL, and high LDL | MERCK CANADA INC. (CA) | 2011-11-22 | — | — | US | disclosed |