SCHEMBL4730622

SCHEMBL4730622

CC/C(=N\OCCc1ccc(C)cc1)c1ccc(OCC(=O)O)cc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.53
MAPT P10636 2/20 0.53
THRB P10828 1/20 0.53
NPSR1 Q6W5P4 1/20 0.45
PPARA Q07869 3/20 0.42
PPARD Q03181 2/20 0.42
PPARG P37231 1/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
MAOB P27338 1/20 0.41
LMNA P02545 1/20 0.41
MCL1 Q07820 1/20 0.41
PARP10 Q53GL7 1/20 0.40
CYP19A1 P11511 1/20 0.40
ESR1 P03372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4727800 0.91 PPARA (0.46) L3MBTL1MAPTTHRBPPARAPPARD
SCHEMBL4727801 0.91 PPARA (0.46) L3MBTL1MAPTTHRBPPARAPPARD
SCHEMBL4729525 0.87 PPARD (0.50) PPARAPPARDPPARGMEN1KMT2A
SCHEMBL4726556 0.87 PPARD (0.50) PPARAPPARDPPARGMEN1KMT2A
SCHEMBL4727914 0.81 MAPT (0.50) L3MBTL1MAPTTHRBNPSR1PPARA
SCHEMBL4727912 0.81 MAPT (0.50) L3MBTL1MAPTTHRBNPSR1PPARA
SCHEMBL4730624 0.79 PPARD (0.44) L3MBTL1PPARAPPARDMEN1GAA
SCHEMBL4727917 0.79 PLA2G4B (0.53) L3MBTL1MAPTPPARAPPARDPPARG
SCHEMBL5423804 0.77 PPARG (0.51) PPARAPPARDPPARGGAAKMT2A
SCHEMBL5423799 0.77 PPARG (0.51) PPARAPPARDPPARGGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO claimed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed