SCHEMBL4730704

SCHEMBL4730704

COc1ccc(-c2cccc(C(=O)N[C@@H](CCN(C)C)c3ccc(Cl)cc3)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4730717 1.00 UTS2R (1.00) UTS2R
Hydrochloric Acid SCHEMBL4783214 0.99 UTS2R (1.00) UTS2R
SCHEMBL4733566 0.93 UTS2R (1.00) UTS2R
SCHEMBL4733064 0.93 UTS2R (1.00) UTS2R
Hydrochloric Acid SCHEMBL4798231 0.92 UTS2R (1.00) UTS2R
SCHEMBL4731218 0.91 UTS2R (1.00) UTS2R
SCHEMBL4733986 0.91 UTS2R (1.00) UTS2R
SCHEMBL4732603 0.90 UTS2R (1.00) UTS2R
SCHEMBL4732734 0.90 UTS2R (1.00) UTS2R
SCHEMBL4729678 0.90 UTS2R (1.00) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008057543-A2 UII-MODULATING COMPOUNDS AND THEIR USE ACADIA PHARMACEUTICALS INC. (US) 2008-05-15 WO claimed
WO-2008057543-A2 UII-MODULATING COMPOUNDS AND THEIR USE ACADIA PHARMACEUTICALS INC. (US) 2008-05-15 WO disclosed