Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.50 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734238 | 0.89 | TDP1 (0.61) | TDP1ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL7179988 | 0.84 | TDP1 (0.81) | TDP1ALDH1A1HPGDSMN1; SMN2NPC1 | |
| Boscalid SCHEMBL29488452 | 0.84 | TDP1 (1.00) | TDP1ALDH1A1HPGDSMN1; SMN2NPC1 | |
| Boscalid SCHEMBL29368300 | 0.84 | TDP1 (1.00) | TDP1ALDH1A1HPGDSMN1; SMN2NPC1 | |
| Boscalid SCHEMBL18517 | 0.84 | TDP1 (1.00) | TDP1ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL8074225 | 0.84 | TDP1 (0.85) | TDP1ALDH1A1HPGDSMN1; SMN2NPC1 | |
| Boscalid SCHEMBL3981357 | 0.83 | TDP1 (0.97) | TDP1ALDH1A1HPGDSMN1; SMN2NPC1 | |
| Boscalid SCHEMBL4336201 | 0.83 | TDP1 (0.97) | TDP1ALDH1A1HPGDSMN1; SMN2NPC1 | |
| Boscalid SCHEMBL3619333 | 0.83 | TDP1 (0.97) | TDP1ALDH1A1HPGDSMN1; SMN2NPC1 | |
| Boscalid SCHEMBL6847778 | 0.83 | TDP1 (0.97) | TDP1ALDH1A1HPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | claimed |
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | disclosed |