Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492276 | 0.79 | CYP1A2 (0.61) | LMNAP2RX7CYP1A2CYP2C9HPGD | |
| SCHEMBL5948063 | 0.79 | EPHX2 (0.79) | LMNACYP1A2CYP2C9CYP2C19EPHX2 | |
| SCHEMBL5754847 | 0.76 | EPHX2 (0.53) | CYP1A2CYP2C9HPGDMAPK1CYP2C19 | |
| SCHEMBL5758650 | 0.74 | CCR3 (0.60) | EPHX2 | |
| SCHEMBL6208905 | 0.74 | TP53 (0.58) | TP53LMNAP2RX7 | |
| SCHEMBL4618812 | 0.74 | EPHX2 (0.79) | LMNACYP1A2CYP2C9CYP2C19EPHX2 | |
| SCHEMBL3879297 | 0.73 | MCHR1 (0.66) | TP53LMNACYP1A2CYP2C19 | |
| SCHEMBL27647648 | 0.73 | TP53 (0.48) | TP53LMNAP2RX7CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL6207067 | 0.73 | TP53 (0.57) | TP53LMNAP2RX7 | |
| SCHEMBL4732616 | 0.71 | UTS2R (1.00) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057543-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2008-05-15 | — | — | WO | claimed |
| WO-2008057543-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2008-05-15 | — | — | WO | disclosed |