Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | WNT3 | P56703 | 1/20 | 0.48 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6600147 | 0.99 | KMT2A (0.75) | KMT2AMEN1ALDH1A1MAPTCA1 | |
| Hydrochloric Acid SCHEMBL6582044 | 0.91 | KMT2A (0.67) | KMT2AMEN1ALDH1A1MAPTCA1 | |
| SCHEMBL2821240 | 0.90 | KMT2A (0.88) | KMT2AMEN1ALDH1A1MAPTCA1 | |
| SCHEMBL30737179 | 0.90 | KMT2A (0.88) | KMT2AMEN1ALDH1A1MAPTCA1 | |
| SCHEMBL34474241 | 0.87 | KMT2A (0.94) | KMT2AMEN1ALDH1A1MAPTCA1 | |
| SCHEMBL12481279 | 0.87 | KMT2A (0.94) | KMT2AMEN1ALDH1A1MAPTCA1 | |
| SCHEMBL15334448 | 0.87 | KMT2A (1.00) | KMT2AMEN1ALDH1A1MAPTCA1 | |
| SCHEMBL14163384 | 0.86 | KMT2A (0.97) | KMT2AMEN1ALDH1A1MAPTCA1 | |
| SCHEMBL2774101 | 0.84 | KMT2A (0.79) | KMT2AMEN1ALDH1A1MAPTCA1 | |
| SCHEMBL13684627 | 0.83 | MEN1 (0.77) | KMT2AMEN1ALDH1A1MAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |
| EP-1379503-A1 | PYRROLIDINE SULFONAMIDES | SmithKline Beecham Corporation (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002079155-A1 | PYRROLIDINE SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-10 | — | — | WO | disclosed |