Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697393 | 0.74 | MAPK1 (0.36) | MAPK1ALDH1A1ALOX15 | |
| SCHEMBL8166385 | 0.73 | MAPK1 (0.42) | MAPK1ALDH1A1ALOX15TDP1KMT2A | |
| SCHEMBL8740112 | 0.73 | MAPK1 (0.57) | MAPK1ALDH1A1ALOX15TDP1KMT2A | |
| SCHEMBL8740114 | 0.73 | MAPK1 (0.57) | MAPK1ALDH1A1ALOX15TDP1KMT2A | |
| SCHEMBL10455289 | 0.72 | MAPK1 (0.41) | MAPK1GAASMN1; SMN2ALDH1A1ALOX15 | |
| SCHEMBL29433631 | 0.71 | MAPK1 (0.55) | MAPK1SMN1; SMN2ALDH1A1ALOX15TDP1 | |
| SCHEMBL27773594 | 0.71 | MAPK1 (0.55) | MAPK1GAASMN1; SMN2ALDH1A1ALOX15 | |
| SCHEMBL4732096 | 0.69 | MAPK1 (0.44) | MAPK1ALDH1A1ALOX15TDP1KMT2A | |
| SCHEMBL10497538 | 0.69 | MAPK1 (0.38) | MAPK1GAASMN1; SMN2ALDH1A1ALOX15 | |
| Propane SCHEMBL10714828 | 0.69 | MAPK1 (0.38) | MAPK1GAASMN1; SMN2ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080250739-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-10-16 | — | — | US | disclosed |
| WO-2008057705-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-05-15 | — | — | WO | disclosed |