⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL1188186 | 1.00 | — | — | |
| Phosphine SCHEMBL28117282 | 0.82 | — | — | |
| Phosphine SCHEMBL28086969 | 0.82 | — | — | |
| Phosphine SCHEMBL28078117 | 0.82 | — | — | |
| Phosphine SCHEMBL9306726 | 0.82 | — | — | |
| Phosphine SCHEMBL27310769 | 0.82 | — | — | |
| Phosphine SCHEMBL28319422 | 0.82 | — | — | |
| Phosphine SCHEMBL11884755 | 0.82 | — | — | |
| Phosphine SCHEMBL10440123 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL28841513 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357292-A1 | MULTI-COORDINATE GOLD-PHOSPHINE COMPOUNDS AND METHOD OF USE | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2023-11-09 | — | — | US | disclosed |
| WO-2008154705-A1 | TRANSDERMAL DELIVERY OF ACTIVE AGENTS | APOLLO LIFE SCIENCES LIMITED (AU) | 2008-12-24 | — | — | WO | disclosed |
| EP-1978997-A1 | TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS | Apollo Life Sciences Limited (AU) | 2008-10-15 | — | — | EP | disclosed |
| WO-2008063662-A2 | GOLD (III) CHLORIDE COMPOSITIONS FOR CANCER | BLACK LION PHARMACEUTICALS (US) | 2008-05-29 | — | — | WO | disclosed |
| US-20070243132-A1 | Transdermal delivery of pharmaceutical agents | APOLLO LIFE SCIENCES LIMITED (AU) | 2007-10-18 | — | — | US | disclosed |
| WO-2007070983-A1 | TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS | APOLLO LIFE SCIENCES LIMITED (AU) | 2007-06-28 | — | — | WO | disclosed |
| US-4125710-A | Method for preparing auranofin | SMITHKLINE CORPORATION (US) | 1978-11-14 | — | — | US | disclosed |
| US-4093719-A | Antiarthritic compositions comprising bis[(trialkyl-phosphine)gold(I)]sulfides and methods of producing antiarthritic activity | SMITHKLINE CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |