SCHEMBL4732409

SCHEMBL4732409

CC(C)(C)[S+]([O-])N[C@@](CC(N)=O)(c1cc(F)cc(C(F)(F)F)c1)c1ccc(Cl)cn1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.56
KCNH2 Q12809 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1182281 1.00 CETP (0.56) CETPKCNH2
SCHEMBL14455490 0.92 CETP (0.57) CETPKCNH2
SCHEMBL1183614 0.92 CETP (0.57) CETPKCNH2
SCHEMBL843471 0.91 CETP (0.63) CETPKCNH2
SCHEMBL1183304 0.89 CETP (0.50) CETPKCNH2
SCHEMBL1183303 0.89 CETP (0.50) CETPKCNH2
SCHEMBL14455496 0.86 CETP (0.50) CETPKCNH2
SCHEMBL1181943 0.85 CETP (0.49) CETPKCNH2
SCHEMBL1181942 0.85 CETP (0.49) CETPKCNH2
SCHEMBL14455491 0.85 CETP (0.56) CETPKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1951673-A2 HETEROCYCLIC CETP INHIBITORS Bristol-Myers Squibb Company (US) 2008-08-06 EP disclosed
WO-2007062314-A2 HETEROCYCLIC CETP INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-05-31 WO disclosed