Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 13/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220604 | 0.85 | SLC28A1 (0.39) | SLC29A1TP53 | |
| SCHEMBL444963 | 0.77 | SLC28A1 (0.42) | HIF1A | |
| SCHEMBL3815627 | 0.75 | SLC29A1 (0.50) | SLC29A1TP53CYP3A4HIF1AABCC4 | |
| SCHEMBL3815635 | 0.75 | SLC29A1 (0.44) | SLC29A1TP53CYP3A4HIF1AABCC4 | |
| SCHEMBL28092439 | 0.75 | SLC28A1 (0.42) | SLC29A1HIF1ASLC28A3 | |
| SCHEMBL29406372 | 0.75 | SLC28A1 (0.42) | SLC29A1HIF1ASLC28A3 | |
| SCHEMBL27220667 | 0.75 | SLC28A1 (0.42) | SLC29A1HIF1ASLC28A3 | |
| SCHEMBL8714851 | 0.74 | ADORA2A (0.44) | SLC29A1TP53CYP3A4HIF1AABCC4 | |
| Nitrobenzene SCHEMBL28322736 | 0.74 | SLC29A1 (0.41) | SLC29A1TP53CYP3A4HIF1AABCC4 | |
| SCHEMBL28042204 | 0.73 | SLC28A1 (0.39) | SLC29A1HIF1ASLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045535-A2 | CONVERTIBLE NUCLEOSIDE DERIVATIVES | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2008-04-17 | — | — | WO | disclosed |