Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | CASR | P41180 | 2/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1329587 | 1.00 | KDM4E (0.54) | KDM4EMEN1KMT2ALMNAHSP90AA1 | |
| SCHEMBL4732908 | 1.00 | KDM4E (0.54) | KDM4EMEN1KMT2ALMNAHSP90AA1 | |
| SCHEMBL8468918 | 1.00 | KDM4E (0.54) | KDM4EMEN1KMT2ALMNAHSP90AA1 | |
| SCHEMBL1329590 | 1.00 | KDM4E (0.54) | KDM4EMEN1KMT2ALMNAHSP90AA1 | |
| SCHEMBL6813373 | 1.00 | KDM4E (0.54) | KDM4EMEN1KMT2ALMNAHSP90AA1 | |
| SCHEMBL6752550 | 0.84 | TDP1 (0.50) | LMNAMAOBTDP1 | |
| SCHEMBL13855361 | 0.80 | MEN1 (0.51) | KDM4EMEN1KMT2ALMNAHSP90AA1 | |
| SCHEMBL1504899 | 0.80 | MEN1 (0.48) | KDM4EMEN1KMT2ALMNAHSP90AA1 | |
| Fumaric Acid SCHEMBL1504896 | 0.80 | CASR (0.51) | KDM4EMEN1KMT2ALMNAHSP90AA1 | |
| Fumaric Acid SCHEMBL1504902 | 0.80 | CASR (0.51) | KDM4EMEN1KMT2ALMNAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008058235-A2 | PROCESSES FOR THE PREPARATION OF CINACALCET | DR. REDDY'S LABORATORIES, LTD. (IN) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008058236-A2 | METHODS FOR PREPARING CINACALCET HYDROCHLORIDE | DR. REDDY'S LABORTORIES, LTD. (IN) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008035381-A2 | PROCESS FOR THE PREPARATION OF AMINE DERIVATIVES AS CALCIMIMETICS | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |