Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 18/20 | 0.70 |
| ▸ | CNR1 | P21554 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14207123 | 0.83 | CNR2 (0.78) | CNR2CNR1 | |
| SCHEMBL4731720 | 0.82 | CNR2 (0.74) | CNR2CNR1 | |
| SCHEMBL4732509 | 0.82 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL4731606 | 0.81 | CNR2 (0.70) | CNR2CNR1 | |
| SCHEMBL4733815 | 0.81 | CNR2 (0.72) | CNR2CNR1 | |
| SCHEMBL14207107 | 0.81 | CNR2 (0.72) | CNR2CNR1 | |
| SCHEMBL4732510 | 0.80 | CNR2 (0.68) | CNR2CNR1 | |
| SCHEMBL4732873 | 0.79 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL4730475 | 0.78 | CNR2 (0.66) | CNR2CNR1 | |
| SCHEMBL4734243 | 0.78 | CNR2 (0.66) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |