SCHEMBL4733407

SCHEMBL4733407

CN(C)CC[C@H](NC(=O)c1cccc(-c2ccccc2)c1)c1ccc2ccccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4733908 1.00 UTS2R (1.00) UTS2R
Hydrochloric Acid SCHEMBL4782246 0.99 UTS2R (1.00) UTS2R
SCHEMBL4733597 0.96 UTS2R (1.00) UTS2R
SCHEMBL4730709 0.96 UTS2R (1.00) UTS2R
SCHEMBL4730439 0.93 UTS2R (1.00) UTS2R
SCHEMBL4733565 0.93 UTS2R (1.00) UTS2R
SCHEMBL4732370 0.92 UTS2R (1.00) UTS2R
SCHEMBL4734216 0.92 UTS2R (1.00) UTS2R
Hydrochloric Acid SCHEMBL4729134 0.92 UTS2R (1.00) UTS2R
SCHEMBL4732998 0.91 UTS2R (1.00) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008057543-A2 UII-MODULATING COMPOUNDS AND THEIR USE ACADIA PHARMACEUTICALS INC. (US) 2008-05-15 WO claimed
WO-2008057543-A2 UII-MODULATING COMPOUNDS AND THEIR USE ACADIA PHARMACEUTICALS INC. (US) 2008-05-15 WO disclosed