Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.69 |
| ▸ | CNR1 | P21554 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730803 | 0.99 | CNR2 (0.69) | CNR2CNR1MEN1KMT2AATM | |
| SCHEMBL4731900 | 0.97 | CNR2 (0.69) | CNR2CNR1ACHEAPPBCHE | |
| SCHEMBL4732274 | 0.96 | CNR2 (0.66) | CNR2CNR1MEN1KMT2AATM | |
| SCHEMBL14207124 | 0.82 | CNR2 (0.47) | CNR2CNR1ACHE | |
| SCHEMBL4732451 | 0.82 | CNR2 (1.00) | CNR2CNR1MEN1KMT2AATM | |
| SCHEMBL4735445 | 0.81 | CNR2 (0.53) | CNR2CNR1ACHE | |
| SCHEMBL4732987 | 0.81 | CNR2 (1.00) | CNR2CNR1MEN1KMT2AATM | |
| SCHEMBL4732822 | 0.81 | CNR2 (0.83) | CNR2CNR1MEN1KMT2AATM | |
| SCHEMBL4735427 | 0.80 | CNR2 (0.66) | CNR2CNR1 | |
| SCHEMBL4732146 | 0.80 | CNR2 (0.66) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |