Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 19/20 | 0.88 |
| ▸ | BCL2 | P10415 | 13/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.53 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29686481 | 0.93 | BCL2L1 (1.00) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL554723 | 0.93 | BCL2L1 (1.00) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL376632 | 0.93 | BCL2L1 (1.00) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL1542046 | 0.90 | BCL2L1 (0.89) | BCL2L1BCL2ALBBCL2L2DOT1L | |
| SCHEMBL27671268 | 0.90 | BCL2L1 (0.89) | BCL2L1BCL2ALBBCL2L2DOT1L | |
| SCHEMBL30404935 | 0.89 | BCL2L1 (0.82) | BCL2L1BCL2ALBBCL2L2DOT1L | |
| SCHEMBL1541685 | 0.89 | BCL2L1 (0.88) | BCL2L1BCL2ALBBCL2L2DOT1L | |
| SCHEMBL3958559 | 0.88 | BCL2L1 (0.80) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL3963890 | 0.88 | BCL2L1 (0.80) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL30405418 | 0.88 | BCL2L1 (0.80) | BCL2L1BCL2ALBBCL2L2DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064116-A2 | METHOD OF PREVENTING OR TREATING ORGAN, HEMATOPOIETIC STEM CELL OR BONE MARROW TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2008-05-29 | — | — | WO | disclosed |