Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.67 |
| ▸ | CNR1 | P21554 | 5/20 | 0.56 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14206966 | 0.80 | CNR2 (1.00) | CNR2CNR1PDCD1CD274 | |
| SCHEMBL4733069 | 0.80 | CNR2 (0.79) | CNR2CNR1 | |
| SCHEMBL4733810 | 0.78 | CNR2 (0.74) | CNR2CNR1 | |
| SCHEMBL4732901 | 0.74 | CNR2 (0.79) | CNR2CNR1PDCD1CD274 | |
| SCHEMBL4732937 | 0.73 | CNR2 (0.68) | CNR2CNR1PDCD1CD274 | |
| SCHEMBL4732273 | 0.73 | CNR2 (0.61) | CNR2CNR1PDCD1CD274 | |
| SCHEMBL4732946 | 0.72 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL4730075 | 0.72 | CNR2 (0.84) | CNR2CNR1PDCD1CD274 | |
| SCHEMBL4730386 | 0.72 | CNR2 (0.66) | CNR2CNR1PDCD1CD274 | |
| SCHEMBL4730649 | 0.72 | CNR2 (1.00) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |