Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 18/20 | 0.76 |
| ▸ | CNR1 | P21554 | 7/20 | 0.72 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14206966 | 0.86 | CNR2 (1.00) | CNR2CNR1PDCD1CD274 | |
| SCHEMBL4734539 | 0.83 | CNR2 (0.84) | CNR2CNR1PDCD1CD274 | |
| SCHEMBL4730649 | 0.83 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL4729137 | 0.83 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL4780813 | 0.83 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL4730790 | 0.82 | CNR2 (0.82) | CNR2CNR1PDCD1CD274 | |
| SCHEMBL4733416 | 0.82 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL4785883 | 0.81 | CNR2 (0.79) | CNR2CNR1PDCD1CD274 | |
| SCHEMBL4729115 | 0.81 | CNR2 (0.78) | CNR2CNR1PDCD1CD274 | |
| SCHEMBL4733803 | 0.80 | CNR2 (0.92) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |