SCHEMBL4733943

SCHEMBL4733943

COc1ccc(C2CCN(C(=O)c3ccc(C)c(NC(=O)c4ccc(N5CCCC5)nc4)c3)CC2)cc1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4732163 0.99 FASN (0.79) FASN
SCHEMBL4734962 0.98 FASN (0.83) FASN
SCHEMBL4732870 0.94 FASN (0.72) FASN
SCHEMBL4737274 0.93 FASN (0.72) FASN
SCHEMBL4732518 0.93 FASN (0.71) FASN
SCHEMBL4734907 0.93 FASN (0.71) FASN
SCHEMBL4733297 0.91 FASN (0.69) FASN
SCHEMBL4785848 0.91 FASN (0.67) FASN
SCHEMBL4733277 0.90 FASN (0.68) FASN
SCHEMBL4795081 0.89 FASN (0.66) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008059214-A1 BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS ASTRAZENECA AB (SE) 2008-05-22 WO disclosed