Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CPA1 | P15085 | 7/20 | 0.51 |
| ▸ | CPA3 | P15088 | 3/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | CPB1 | P15086 | 1/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 3/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442519 | 0.85 | EPHX2 (0.49) | CYP1A2CPA1CPA3EPHX2 | |
| SCHEMBL9105287 | 0.85 | KDM4E (0.48) | CYP1A2GRIK1GRIK2 | |
| SCHEMBL9105279 | 0.85 | KDM4E (0.48) | CYP1A2GRIK1GRIK2 | |
| SCHEMBL3219589 | 0.85 | CYP1A2 (0.54) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL6790355 | 0.84 | CYP1A2 (0.61) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL27377152 | 0.80 | CYP1A2 (0.70) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL6791072 | 0.79 | CYP1A2 (0.59) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL12099047 | 0.78 | GRIK1 (0.58) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2229237 | 0.78 | GRIK1 (0.58) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2754220 | 0.78 | GRIK1 (0.58) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053340-A1 | A COMBINATION PRODUCT COMPRISING AT LEAST ONE LIPID SUBSTITUTED IN THE ALPHA POSITION AND AT LEAST ONE HYPOGLYCEMIC AGENT | PRONOVA BIOPHARMA NORGE AS (NO) | 2008-05-08 | — | — | WO | disclosed |