Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.60 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 14/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179288 | 0.77 | GBA1 (0.62) | GBA1AOC3HCAR3MYCKMT2A | |
| SCHEMBL10622006 | 0.77 | GBA1 (0.62) | GBA1AOC3HCAR3MYCKMT2A | |
| SCHEMBL2307310 | 0.76 | APP (0.40) | GBA1SMN1; SMN2 | |
| SCHEMBL1432871 | 0.75 | GBA1 (0.60) | GBA1AOC3HCAR3MYCKMT2A | |
| SCHEMBL8430068 | 0.75 | GBA1 (0.60) | GBA1AOC3HCAR3MYCSMN1; SMN2 | |
| SCHEMBL17316578 | 0.75 | GBA1 (1.00) | GBA1AOC3HCAR3MYCKMT2A | |
| SCHEMBL7096589 | 0.75 | GBA1 (0.60) | GBA1AOC3HCAR3MYCKMT2A | |
| SCHEMBL2793295 | 0.75 | GBA1 (0.60) | GBA1AOC3HCAR3MYCKMT2A | |
| SCHEMBL17274025 | 0.75 | GBA1 (0.60) | GBA1AOC3HCAR3MYCKMT2A | |
| SCHEMBL30175373 | 0.75 | GBA1 (0.60) | GBA1AOC3HCAR3MYCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| CN-101379041-A | Tricyclic N-heteroaryl-amide derivatives containing benzimidazole structural units, their preparation and their therapeutic use | SANOFI AVENTIS (FR) | 2009-03-04 | — | — | CN | disclosed |