SCHEMBL4734203

SCHEMBL4734203

CC(C)c1ccc(C(=O)OC(=O)c2cc(O)c(O)c(O)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.51
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
NFKB1 P19838 1/20 0.50
XDH P47989 1/20 0.50
GFER P55789 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
FUT7 Q11130 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
SERPINE1 P05121 5/20 0.45
PRSS1 P07477 1/20 0.44
ACR P10323 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9699988 0.86 CYP2C9 (0.52) TYRKDM4ELMNAPOLBL3MBTL1
SCHEMBL28275533 0.86 KDM4E (0.59) TYRKDM4ELMNAPOLBGAA
SCHEMBL4732803 0.82 NSD2 (0.63) TYRKDM4ELMNAPOLBGAA
SCHEMBL1668506 0.80 KDM4E (0.67) KDM4ELMNAPOLBGAANFKB1
SCHEMBL9699992 0.79 TSHR (0.50) LMNAPOLBPRSS1ACRNPC1
SCHEMBL28810687 0.79 KDM4E (0.59) TYRKDM4ELMNAPOLBGAA
SCHEMBL4734206 0.78 TYR (0.56) TYRL3MBTL1SERPINE1ESR1
SCHEMBL6754307 0.77 NSD2 (0.65) TYRKDM4ELMNAPOLBGAA
SCHEMBL873056 0.77 CYP2C9 (0.47) TYRKDM4ELMNAPOLBL3MBTL1
SCHEMBL28121664 0.75 NSD2 (0.62) TYRKDM4ELMNAPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008065527-A2 GALLIC ACID ESTERS OF FRAGRANT ALCOHOLS GHISALBERTI CARLO (BR) 2008-06-05 WO disclosed