SCHEMBL4734749

SCHEMBL4734749

Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)c1ccnc(N2CCNC(=O)C2)c1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4734562 0.92 FASN (0.80) FASN
SCHEMBL14210103 0.91 FASN (0.55) FASN
SCHEMBL4734369 0.90 FASN (0.82) FASN
SCHEMBL4734044 0.89 FASN (0.81) FASN
SCHEMBL4734396 0.88 FASN (0.72) FASN
SCHEMBL4735346 0.88 FASN (0.73) FASN
SCHEMBL4784792 0.88 FASN (0.71) FASN
SCHEMBL4784776 0.85 FASN (0.90) FASN
SCHEMBL4733661 0.85 FASN (0.71) FASN
SCHEMBL4734679 0.84 FASN (0.72) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008059214-A1 BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS ASTRAZENECA AB (SE) 2008-05-22 WO claimed
WO-2008059214-A1 BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS ASTRAZENECA AB (SE) 2008-05-22 WO disclosed