Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 9/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4481349 | 1.00 | SSTR3 (0.56) | SSTR3SCN9ASMN1; SMN2KDM4EGAA | |
| SCHEMBL4735123 | 1.00 | SSTR3 (0.56) | SSTR3SCN9ASMN1; SMN2KDM4EGAA | |
| SCHEMBL4486701 | 1.00 | SSTR3 (0.56) | SSTR3SCN9ASMN1; SMN2KDM4EGAA | |
| SCHEMBL14038227 | 1.00 | SSTR3 (0.56) | SSTR3SCN9ASMN1; SMN2KDM4EGAA | |
| SCHEMBL4490343 | 0.97 | SSTR3 (0.59) | SSTR3SCN9ASMN1; SMN2KDM4EGAA | |
| SCHEMBL4487139 | 0.97 | SSTR3 (0.59) | SSTR3SCN9ASMN1; SMN2KDM4EGAA | |
| SCHEMBL4735141 | 0.97 | SSTR3 (0.59) | SSTR3SCN9ASMN1; SMN2KDM4EGAA | |
| SCHEMBL4735143 | 0.97 | SSTR3 (0.59) | SSTR3SCN9ASMN1; SMN2KDM4EGAA | |
| SCHEMBL4496471 | 0.96 | SSTR3 (0.58) | SSTR3SCN9ASMN1; SMN2KDM4EGAA | |
| SCHEMBL4488010 | 0.96 | SSTR3 (0.58) | SSTR3SCN9ASMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073982-A2 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | ANADYS PHARMACEUTICALS, INC. (US) | 2008-06-19 | — | — | WO | disclosed |