Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135790 | 0.89 | MEN1 (0.39) | — | |
| SCHEMBL28679396 | 0.89 | MEN1 (0.39) | — | |
| SCHEMBL2000871 | 0.89 | MEN1 (0.39) | — | |
| SCHEMBL7142279 | 0.88 | FFAR4 (0.49) | FFAR4FFAR1PTPN1GSTK1CYP1A2 | |
| SCHEMBL7134435 | 0.88 | FFAR4 (0.49) | FFAR4FFAR1PTPN1GSTK1CYP1A2 | |
| SCHEMBL17782931 | 0.88 | FFAR4 (0.49) | FFAR4FFAR1PTPN1GSTK1CYP1A2 | |
| SCHEMBL9649626 | 0.88 | FFAR4 (0.49) | FFAR4FFAR1PTPN1GSTK1CYP1A2 | |
| SCHEMBL36574 | 0.85 | FFAR4 (0.51) | FFAR4FFAR1PTPN1GSTK1GPR84 | |
| SCHEMBL29790257 | 0.81 | MEN1 (0.41) | FOLH1FFAR4FFAR1CYP1A2CYP3A4 | |
| SCHEMBL4735293 | 0.81 | FOLH1 (0.39) | FOLH1GSTK1PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075887-A1 | IMMOBILIZATION LINKERS FOR BIOMOLECULES | DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2008-06-26 | — | — | WO | disclosed |