Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3522831 | 1.00 | EGFR (0.65) | EGFRERBB2 | |
| SCHEMBL3525133 | 1.00 | EGFR (0.65) | EGFRERBB2 | |
| SCHEMBL3520160 | 0.93 | EGFR (0.59) | EGFRERBB2 | |
| SCHEMBL6111518 | 0.93 | EGFR (0.59) | EGFRERBB2 | |
| SCHEMBL4732086 | 0.93 | EGFR (0.62) | EGFRERBB2 | |
| SCHEMBL3519411 | 0.93 | EGFR (0.62) | EGFRERBB2 | |
| SCHEMBL3521773 | 0.93 | EGFR (0.63) | EGFRERBB2 | |
| SCHEMBL3521645 | 0.92 | EGFR (0.65) | EGFRERBB2 | |
| SCHEMBL3525143 | 0.92 | EGFR (0.69) | EGFRERBB2 | |
| SCHEMBL3524444 | 0.92 | EGFR (0.63) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622620-B1 | QUINAZOLINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | EP | disclosed |