Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222189 | 0.77 | POLB (0.37) | POLB | |
| SCHEMBL3222193 | 0.77 | POLB (0.37) | POLB | |
| SCHEMBL16912704 | 0.73 | POLB (0.36) | POLBCTSLCTSBCTSHCTSK | |
| SCHEMBL21149652 | 0.73 | POLB (0.36) | POLBCTSLCTSBCTSHCTSK | |
| SCHEMBL28603652 | 0.73 | POLB (0.36) | POLBCTSLCTSBCTSHCTSK | |
| SCHEMBL16912703 | 0.73 | POLB (0.36) | POLBCTSLCTSBCTSHCTSK | |
| SCHEMBL3216743 | 0.73 | POLB (0.33) | POLB | |
| SCHEMBL3216751 | 0.73 | POLB (0.33) | POLB | |
| SCHEMBL28966629 | 0.72 | POLB (0.35) | POLBCTSLCTSBCTSHCTSK | |
| SCHEMBL27893659 | 0.72 | POLB (0.35) | POLBCTSLCTSBCTSHCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074035-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2008-06-19 | — | — | WO | disclosed |