SCHEMBL4735833

SCHEMBL4735833

Cc1ccc(C(=O)N2CCC(O)(c3ccc(C#N)cc3)CC2)cc1NC(=O)NC(C)C.Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)NCCCC(=O)OC(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4201404 0.89 FASN (0.57) FASN
SCHEMBL4735837 0.85 FASN (0.48) FASN
SCHEMBL4203530 0.82 FASN (0.59) FASN
SCHEMBL4204884 0.82 FASN (0.59) FASN
SCHEMBL4198155 0.81 FASN (0.65) FASN
SCHEMBL4202424 0.81 FASN (0.60) FASN
SCHEMBL4201033 0.81 FASN (0.63) FASN
SCHEMBL4209220 0.80 FASN (0.76) FASN
SCHEMBL4203646 0.79 FASN (0.60) FASN
SCHEMBL4205009 0.79 FASN (0.62) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075064-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO disclosed