SCHEMBL4735836

SCHEMBL4735836

[CH2]CS(=O)(=O)Nc1cc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)ccc1C

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4176263 0.93 FASN (0.65) FASN
SCHEMBL4169807 0.92 FASN (0.62) FASN
SCHEMBL4172371 0.91 FASN (0.59) FASN
SCHEMBL4184050 0.91 FASN (0.62) FASN
SCHEMBL4175305 0.91 FASN (0.64) FASN
SCHEMBL4183556 0.91 FASN (0.61) FASN
SCHEMBL4180737 0.91 FASN (0.64) FASN
SCHEMBL4175604 0.90 FASN (0.60) FASN
SCHEMBL4179992 0.90 FASN (0.61) FASN
SCHEMBL4184200 0.90 FASN (0.60) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075070-A1 SULFONAMIDE DERIVATIVES FOR THERAPEUTIC USE AS FATTY ACID SYNTHASE INHIBITORS ASTRAZENECA AB (SE) 2008-06-26 WO disclosed