SCHEMBL4735904

SCHEMBL4735904

CCCN(c1ccc(C(=O)Nc2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)ccc2C)cn1)n1ccnc1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4732150 0.90 FASN (0.55) FASN
SCHEMBL4733263 0.85 FASN (0.76) FASN
SCHEMBL4732466 0.85 FASN (0.75) FASN
SCHEMBL4734169 0.83 FASN (0.72) FASN
SCHEMBL4734897 0.81 FASN (0.80) FASN
SCHEMBL4735404 0.81 FASN (0.79) FASN
SCHEMBL4734536 0.81 FASN (0.76) FASN
SCHEMBL4732219 0.80 FASN (0.73) FASN
SCHEMBL4734728 0.80 FASN (0.73) FASN
SCHEMBL4735338 0.80 FASN (0.72) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008059214-A1 BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS ASTRAZENECA AB (SE) 2008-05-22 WO claimed