Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 12/20 | 0.42 |
| ▸ | UBE2M | P61081 | 2/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731303 | 0.86 | FASN (0.46) | FASNPROKR1CNR1 | |
| SCHEMBL4734896 | 0.85 | FASN (0.45) | FASNPROKR1CNR1 | |
| SCHEMBL4734404 | 0.85 | FASN (0.45) | FASNPROKR1CNR1 | |
| SCHEMBL4786265 | 0.83 | FASN (0.44) | FASNPROKR1CNR1 | |
| SCHEMBL4731986 | 0.82 | FASN (0.46) | FASNPROKR1CNR1 | |
| SCHEMBL4734716 | 0.80 | FASN (0.49) | FASNPROKR1CNR1 | |
| SCHEMBL4736874 | 0.79 | FASN (0.53) | ALDH1A1KMT2AFASNPROKR1 | |
| SCHEMBL4732265 | 0.79 | FASN (0.46) | KMT2AFASNPROKR1CNR1 | |
| SCHEMBL4780610 | 0.79 | FASN (0.45) | FASNPROKR1 | |
| SCHEMBL4733770 | 0.78 | FASN (0.51) | ALDH1A1FASNPROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |