SCHEMBL473626

SCHEMBL473626

COC(=O)[C@H]1CC[C@H](N)CC1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.44
PPM1B O75688 1/20 0.44
PTPN1 P18031 1/20 0.44
PPP1CC P36873 1/20 0.44
CHRNB2 P17787 2/20 0.42
CHRNA4 P43681 2/20 0.42
CHRNB4 P30926 1/20 0.42
CHRNA3 P32297 1/20 0.42
CHRNA7 P36544 1/20 0.42
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
MMP2 P08253 1/20 0.40
ANPEP P15144 1/20 0.40
BRD4 O60885 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL363035 1.00 TP53 (0.47) TP53SMN1; SMN2PPM1BPTPN1PPP1CC
SCHEMBL380500 1.00 TP53 (0.47) TP53SMN1; SMN2PPM1BPTPN1PPP1CC
Hydrochloric Acid SCHEMBL363034 0.98 TP53 (0.46) TP53SMN1; SMN2PPM1BPTPN1PPP1CC
Hydrochloric Acid SCHEMBL363033 0.98 TP53 (0.46) TP53SMN1; SMN2PPM1BPTPN1PPP1CC
Hydrochloric Acid SCHEMBL1178819 0.98 TP53 (0.46) TP53SMN1; SMN2PPM1BPTPN1PPP1CC
SCHEMBL24475220 0.92 SMN1; SMN2 (0.47) TP53SMN1; SMN2PPM1BPTPN1PPP1CC
SCHEMBL22096230 0.92 SMN1; SMN2 (0.51) TP53SMN1; SMN2PPM1BPTPN1PPP1CC
SCHEMBL19910371 0.90 SMN1; SMN2 (0.54) TP53SMN1; SMN2PPM1BPTPN1PPP1CC
Sulfuric Acid SCHEMBL27596525 0.88 TP53 (0.47) TP53SMN1; SMN2PPM1BPTPN1PPP1CC
SCHEMBL13245964 0.88 TP53 (0.40) TP53SMN1; SMN2PPM1BPTPN1PPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12616682-B2 1-H-pyrrolo[2,3-c]pyridine compounds ACERTA PHARMA B.V. (NL) 2026-05-05 US disclosed
EP-4724430-A1 CONDENSED AZINES AS INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE Flagship Pioneering Innovations VI, LLC (US) 2026-04-15 EP disclosed
EP-4423075-B1 CCR6 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2026-03-25 EP disclosed
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
US-20250360112-A1 1-H-PYRROLO[2,3-c]PYRIDINE COMPOUNDS ACERTA PHARMA BV (NL) 2025-11-27 US disclosed
EP-4620951-A1 MEMANTINE UREA DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN PREPARATION OF MEDICAMENT FOR TREATING SOLUBLE EPOXIDE ENZYME-MEDIATED DISEASES Shenyang Pharmaceutical University (CN) 2025-09-24 EP disclosed
EP-4608810-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS Septerna, Inc. (US) 2025-09-03 EP disclosed
WO-2025059577-A1 SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS ATAVISTIK BIO, INC. (US) 2025-03-20 WO disclosed
US-20250011313-A1 CCR6 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2025-01-09 US disclosed
WO-2024254396-A1 CONDENSED AZINES AS INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE FLAGSHIP PIONEERING INNOVATIONS, VI, LLC (US) 2024-12-12 WO disclosed
US-5880284-A HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS DR. KARL THOMAE GMBH (DE) 1999-03-09 US disclosed
US-5821240-A ENZYME INHIBITORS, SIGNAL INHIBITORS FOR ANTIINFLAMMATORY AGENTS, ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS AND HORMONE INHIBITORS DR. KARL THOMAE GMBH (DE) 1998-10-13 US disclosed
US-5817677-A ANTITHROMBOSIS AGENTS DR. KARL THOMAE GMBH (DE) 1998-10-06 US disclosed
US-5707989-A ANTITUMOR AGENTS, INHIBITING SIGNAL TRANSDUCTION MEDIATED BY TYROSINE KINASES DR. KARL THOMAE GMBH (DE) 1998-01-13 US disclosed
US-5681841-A PREVENTION CELL AGGREGATION KARL THOMAE GMBH (DE) 1997-10-28 US disclosed
US-5563268-A FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1996-10-08 US disclosed
US-5442064-A Anticoagulants, antiagglomerants DR. KARL THOMAE GMBH (DE) 1995-08-15 US disclosed
US-5418233-A FOR INHIBITING CELL AGGREGATION KARL THOMAE GMBH (DE) 1995-05-23 US disclosed
CN-1092769-A Cyclic urea derivatives, the method that contains the pharmaceutical composition of these compounds and prepare them THOMAE GMBH DR K (DE) 1994-09-28 CN disclosed
CN-1087904-A Carboxylic acid derivative, the pharmaceutical composition that contains these compounds with and preparation method thereof KRAL THOMAE GMBH (DE) 1994-06-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011313-A1 CCR6 RECEPTOR MODULATORS CCR6, CCR1, CCR4 TP53 3012/4885SMN1; SMN2 3217/4885PPM1B 2097/4885
US-12616682-B2 1-H-pyrrolo[2,3-c]pyridine compounds MEN1, PKD1, PKD2 TP53 4094/4885SMN1; SMN2 121/4885PPM1B 689/4885
US-20250360112-A1 1-H-PYRROLO[2,3-c]PYRIDINE COMPOUNDS MEN1, PKD1, ADCYAP1R1 TP53 1914/4885SMN1; SMN2 220/4885PPM1B 519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.