Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 9/20 | 0.57 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | F3 | P13726 | 3/20 | 0.50 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.50 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.50 |
| ▸ | PTPRC | P08575 | 2/20 | 0.50 |
| ▸ | PTPRF | P10586 | 2/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | ACP1 | P24666 | 2/20 | 0.50 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.50 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.50 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.50 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2984032 | 0.86 | PTPN1 (0.61) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL5799375 | 0.85 | PTPN1 (0.68) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL3291507 | 0.84 | USP2 (0.65) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL4735932 | 0.84 | PTPN1 (0.61) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL4736766 | 0.82 | PTPN1 (0.83) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL3871334 | 0.80 | PTPN1 (0.74) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL4734338 | 0.79 | PTPN1 (0.68) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL5799239 | 0.78 | PTPN1 (0.66) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL5667958 | 0.78 | PTPN1 (0.66) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL4736386 | 0.78 | PTPN1 (0.77) | PTPN1PTPN2AKR1B10AKR1B1F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071169-A2 | METHOD FOR THE PRODUCTION OF SPECIFIC INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE, IN PARTICULAR TYPE 1 WITH BASIC NOR-OLEANAN OR NOR-URSAN FRAMEWORKS | UNIVERSITÄTSKLINIKUM SCHLESWIG-HOLSTEIN (DE) | 2008-06-19 | — | — | WO | disclosed |