SCHEMBL4736612

SCHEMBL4736612

Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1N(C(N)=O)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.51
FASN P49327 19/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4738385 0.92 FASN (0.48) FASN
SCHEMBL4198328 0.86 FASN (0.50) FASN
SCHEMBL4203630 0.85 FASN (0.52) FASN
SCHEMBL4196814 0.85 FASN (0.52) FASN
SCHEMBL4189227 0.85 FASN (0.52) FASN
SCHEMBL4739741 0.84 PARP10 (0.46) GPR119
SCHEMBL4202422 0.80 FASN (0.50) FASN
SCHEMBL4203895 0.79 FASN (0.51) FASN
SCHEMBL4210050 0.79 FASN (0.53) FASN
SCHEMBL4782403 0.79 FASN (0.45) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075064-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO disclosed